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Anthrax Vaccines

A Better Vaccine is Needed

Our anthrax vaccine product candidates are being developed as next generation vaccines for the prevention of anthrax disease following inhalation of pathogen spores. Our anthrax vaccines are designed to provide protection with fewer doses and better tolerability than the currently licensed vaccine.

Our NasoShield anthrax vaccine candidate is being developed as the ultimate anthrax vaccine. NasoShield is based on our RespirVec technology to provide protection following a single intranasal administration as opposed to multiple injections. Based on head-to-head results from studies performed in gold-standard preclinical models, NasoShield provided more rapid and consistent protection when compared to the currently approved anthrax vaccine, both potential key advantages for presumed use in a bioterrorism emergency. A Phase 1 study of the safety and immunogenicity of NasoShield is currently enrolling subjects at two U.S. sites.

Key Advantages of Anthrax Vaccines

SparVax-L is being developed as a second generation, highly purified recombinant anthrax vaccine that requires only two vaccinations for protection. SparVax-L is further differentiated by its remarkable stability profile that is well-suited for stockpiling in the Strategic National Stockpile.

Our NasoShield anthrax vaccine candidate is being developed as the ultimate anthrax vaccine. NasoShield is based on our RespirVec technology to provide protection following a single intranasal administration as opposed to multiple injections. Based on head-to-head results from studies performed in gold-standard preclinical models, NasoShield provided more rapid and consistent protection when compared to the currently approved anthrax vaccine, both potential key advantages for presumed use in a bioterrorism emergency.

Our Partner

Our anthrax vaccine candidates are being developed with support from the United States Government Department of Health and Human Services. SparVax-L is being developed with the support of the National Institute of Allergy and Infectious Diseases, and NasoShield is being developed with the support of the Biomedical Advanced Research and Development Authority.